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PUBLICATIONS

2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010

    2024
  1. Osman, E.A., Rynes, T.P.; Wang, Y.L.; Mruk, K.; McKeague, M. Non-invasive single cell aptasensing in live cells and animals. Chemical Science. 2024, 15, 4770-4778.
  2. Kovecses, O.; Mercier, F.E.; McKeague, M. Nucleic acid therapeutics as differentiation agents for myeloid leukemias. Leukemia. 2024, 38, 1441-1454.
  3. Rivera, M.; Ayon, O.S.; Diaconescu-Grabari, S.; Pottel, J.; Moitessier, N.; Mittermaier, A.; McKeague, M. A sensitive and scalable fluorescence anisotropy single stranded RNA targeting approach for monitoring riboswitch conformational states. Nucleic Acids Research. 2024, 52, 3164-3179.

    4. 2023
  4. Ayon, O.S.; McKeague, M. Surface plasmon resonance assay for screening diverse aptamer-target interactions. Aptamers. 2023, 7, 7-12.
  5. DeRosa, M.C.; Lin, A.; Mallikaratchy, P.; McConnell, E.M.; McKeague, M.; Patel, R.; Shigdar, S. In vitro selection of aptamers and their applications. Nature Reviews Methods Primers. 2023, 3, 55.
  6. Maru, B., Messikommer, A., Huang, M., Seipel, K., Kovecses, O., Valk, P.J.M., Theocharides, A.P.A., Mercier, F.E., Pabst, T., McKeague, M., Luedtke, N. PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy. Cell Reports Medicine. 2023, 4, 101191362
  7. Jiang, Y.; Mingard, C.; Huber, S.; Takhaveev, V.; McKeague, M.; Kizaki, S.; Ziegler, N.; Schneider, M.; Hürlimann, V.; Hoeng, J.; Sierro, N.; Ivanov, N.; Sturla, S.J. Quantification and Mapping of Alkylation in the Human Genome Reveal Single Nucleotide Resolution Precursors of Mutational Signatures. ACS Central Science. 2023, 3, 362–372.

    8. 2022
  8. McKeague, M.; Calzada, V.; Cerchia, L.; DeRosa, M.C.; Heemstra, J.M.; Janjic, N.; Johnson, P.E.; Kraus, L.; Limson, J.; Mayer, G.; Nilsen-Hamilton, M.; Porciani, D.; Sharma, T.K.; Suess, B.; Tanner, J.A.; Shigdar, S. The minimum aptamer publication standards (MAPS guidelines) for de novo aptamer selection. Aptamers. 2022.
  9. Forder, M.; McKeague, M. Tuning Aptamer-Switching for Biosensing Malarial Proteins. MSURJ. 2022.
  10. Robinson, K.A.; Lee, S.Y.; Friedman, S.; Christiaans, E.; McKeague, M.; Pavelka, L.; Sirjoosingh, P. You know what, I can do this”: Heterogeneous Joint Trajectories of Expectancy for Success and Attainment Value in Chemistry. Contemporary Educational Psychology. 2022. 69, 102055.

    11. 2021
  11. Maru, B.; Nadeau, L.; McKeague, M. Enhancing CAR-T Cell Therapy with Functional Nucleic Acids. ACS Pharmacol. Transl. Sci. 2021, 4, 6, 1716–17273.
  12. Bechu, A.; Liao, J.; Huang, C.; Ahn, C.; McKeague, M.; Ghoshal, S.; Moores, A. Cadmium-Containing Quantum Dots Used in Electronic Displays: Implications for Toxicity and Environmental Transformations. ACS Appl. Nano Mater. 2021. 8: 8417-8428.
  13. Hirka, S; McKeague, M. Quantification of aptamer-protein binding with fluorescence anisotropy Aptamers. 2021, 5.

    14. 2020
  14. Krebs, J.; McKeague, M. Green toxicology: connecting green chemistry and modern toxicology Chemical Research in Toxicology. 2020, 33, 2919–2931.
  15. Mingard, C.; Wu, J.; McKeague, M.; Sturla, S.J. Next-generation DNA damage sequencing Chemical Society Reviews. 2020, 49, 7354-7377.
  16. Wang, L.; McKeague, M. Aptamers in the pursuit of COVID-19 management Aptamers. 2020, 4, 1-2.
  17. Oteng, E.K.; Gu, W.; McKeague, M. High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes Scientific Reports. 2020, 10, 9706.
  18. Oteng, E.K.; Gu, W.; McKeague, M. High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes. Scientific Reports. 2020, 10, 9706.

    19. 2019
  19. Xiang, J.S.; Kaplan, M.; Dykstra, P.; Hinks, M.; McKeague, M.; Smolke, C.D. Massively Parallel RNA Device Engineering in Mammalian Cells with RNA-Seq and FACS-Seq. Nature Communications 2019. 10, 4327.
  20. Shigdar, S.; Johnson, P.E.; Pietruschka, G.; Legen, T.; Mayer, G.; McKeague, M. Aptamers 2019-a conference update. Aptamers 2019, 3, 1-3.
  21. Smith, M.; McKeague, M.; DeRosa, M.C. Synthesis, Transfer, and Characterization of Core-Shell Gold-Coated Magnetic Nanoparticles MethodsX. 2019.
  22. Kraus, A.; McKeague, M.; Seiwert, N.; Nagel, G.; Minneker, V.; Geisen, S. Zeigler, N.; Trantakis, I.A.; Kaina, B.; Thomas, A.D.; Sturla, S.J.; Fahrer, J. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O6-methylguanine in vivo. Arch Toxicol. 2019, 93, 559–572.
  23. Lam, J.; McKeague, M. Dietary modulation of mitochondrial DNA damage: Implications in ageing and associated diseases. The Journal of Nutritional Biochemistry 2019, 63, 1–10.

    24. 2018

  24. McKeague, M.; Otto, C.; Angelov, T.; Räz, M.H.; Sturla, S.J. 2018. Base-pairing partner modulates alkylguanine alkyltransferase ACS Chemical Biology 2018, 13 (9), 2534-2541.
  25. Wu, J.; McKeague, M.; Sturla, S.J. Nucleotide-resolution genome-wide mapping of oxidative DNA damage by click-code-seq, JACS. 2018, 140 (31), 9783-9787.
  26. DeGirolamo, A.;, McKeague, M.; Pascale, M.; Cortese, M.; DeRosa, M.C. Chapter 3: Immobilization of aptamers on substrates. Aptamers for Analytical Applications: Affinity Optimization and Method Design. Wiley-VCH Verlag GmbH & Co. (Ed) 2018, 85-126.
  27. Tanner, J.A.; Ismail, S.I.; Shigdar, S.; DeRosa, M.C.; Hahn, U.; Johnson, P.E.; Suess, B.; McKeague, M. Aptamers 2018-a conference update Aptamers. 2018, 2.
  28. Dahlmann, H.A.; Berger, F.D.; Kung, R.W.; Wyss, L.A.; Gubler, I.; McKeague, M.; Wetmore, S.D.; Sturla, S.J. Fluorescent Nucleobase Analogues with Extended Pi Surfaces Stabilize DNA Duplexes Containing O6‐Alkylguanine Adducts Helvetica Chimica Acta.
  29. Dörsam, B.; Seiwert, N.; Foersch, S.; Stroh, S.; Nagel, G.; Begaliew, G.; Diehl, E.; Kraus, A.; McKeague, M.; Minneker, V.; Roukos, V.; Reißig, V.; Waisman, A.; Moehler, M.; Stier, A.; Mangerich, A.; Dantzer, F.; Kaina, B.; Fahrer, J. PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression, PNAS. 2018, 115, E4061-E4070.
  30. Awwad, A.M.; McKeague, M. Riboswitches and synthetic aptamers: a head-to-head comparison Aptamers. 2018, 2.
  31. Henri, J.; McKeague, M.; Johnson, P.E.; Suess, B.; Nakamura, Y.; Nilsen-Hamilton, M.; Pastor, F.; Hahn, U.; Bunka, D.; Shigdar, S. Aptamers 2017 at Oxford Aptamers. 2018, 2.

    32. 2017

  32. Ruscito, A.; McConnell, E.M.; Koudrina, A.; Ranganathan, V.; Mattice, C.; Hunt, V.; McKeague, M.; DeRosa, M.C. In vitro selection and characterization of DNA aptamers to a small molecule target Current Protocols in Chemical Biology. 2017, 9, 233-268.
  33. McKeague, M. Aptamers for DNA damage and repair International Journal of Molecular Sciences. 2017, 18 (10), 2212.
  34. Alsaafin, A.; McKeague, M. Functional nucleic acids as in vivo metabolite and ion biosensors Biosensors and Bioelectronics, 2017, 94, 94–106.

    35. 2016

  35. McKeague, M.; Ranganathan, V.; De Girolamo, A.; Valenzano, S.; Pascale, M.; Smith, M.; DeRosa, M.C. Comparison of in-solution biorecognition properties of aptamers against ochratoxin A, Toxins. 2016, 8 (11), 336-348.
  36. Wang, Y-H.; McKeague, M.; Hsu, T.M.; Smolke, C.D. Design and construction of generalizable RNA-protein hybrid controllers by level-matched genetic signal amplification Cell Systems. 2016, 3 (6), 549–562.
  37. McKeague, M.; Wang, Y-H.; Cravens, A.; Win, M.N.; Smolke, C.D. Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines Metabolic Engineering. 2016, 38, 191–203.
  38. Valenzano, S.; De Girolamo, A.; DeRosa, M.C.; McKeague, M.; Schena, R.; Catucci, L.; Pascale, M. Screening and Identification of DNA aptamers to tyramine using in vitro selection and high-throughput sequencing. ACS Combinatorial Science. 2016, 18 (6), 302–313.
  39. McKeague, M.; Wong, R.S.; Smolke, C.D. Opportunities in the design and application of RNA for gene expression control Nucleic Acids Research. 2016, 44 (7),2987-2999

    40. 2015

  40. McKeague, M.; Wang, Y-H.; Smolke, C.D. In vitro screening and in silico modeling of RNA-based gene expression control ACS Chemical Biology. 2015, 10 (11), 2463–2467.
  41. McKeague, M.; McConnell, E.M.; Cruz-Toledo, J.; Bernard, E.D.; Pach, A.; Zhang, X.; Beking, M.; Francis, T.; Giamberardino, A.; Cabecinha, A.; Ruscito, A.; Aranda-Rodriguez, R.; Dumontier, M.; DeRosa, M.C. Analysis of in vitro aptamer selection parameters. Journal of Molecular Evolution. 2015, 81(5), 150-161.
  42. Frost, N.R.; McKeague, M.; Falcioni, D.; DeRosa, M.C. An in solution assay for parallel interrogation of structure and affinity of small molecule-binding aptamers, Analyst. 2015, 140 (8) 6643–6651.
  43. McKeague, M.; De Girolamo, A.; Valenzano, S.; Pascale, M.; Ruscito, A.; Ranganathan, V.; Frost, N.; Hill, K.; Smith, M.; McConnell, E.; DeRosa, M.C.Comprehensive analytical comparison of strategies used for small molecule aptamer evaluation, Analytical Chemistry. 2015, 87 (17), 8608–8612.

    44. 2014

  44. Chang, A.L.; McKeague, M.; Smolke, C.D. Facile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance In: Burke-Aguero, D., editor. Methods in Enzymology. 2014, 549, 451-466.
  45. McKeague, M.; DeRosa, M.C. Aptamers and SELEX: Tools for the development of transformative molecular recognition technology, Aptamers and Synthetic Antibodies. 2014, 1 (1), 12-16.
  46. McKeague, M.; Ranganathan, V.; Hill, K.; Bardozy, V.; Mezaros, T.; DeRosa, M.C. Selection and characterization of a novel DNA aptamer For label-free fluorescence biosensing of ochratoxin A, Toxins. 2014, 6 (8), 2435-2452.
  47. Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. Kinetic and equilibrium binding characterization of aptamers to small molecules using a label-free, sensitive, and scalable Platform, Analytical Chemistry. 2014, 86 (7), 3273–3278.

    48. 2013

  48. Mastronardi, E.; McKeague, M.; Monreal, C.; DeRosa, M.C. Development and application of crop exudate specific aptamers, Journal of Biomolecular Structure and Dynamics. 2013, 31 (1), 89.
  49. McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. Development of a DNA aptamer for direct and selective homocysteine detection in human serum, RSC Advances. 2013, 3 (46), 24415-24422.

    50. 2012

  50. McKeague, M.; DeRosa, M.C. Challenges and opportunities for small molecule aptamer development, Journal of Nucleic Acids. 2012.
  51. Cruz-Toledo, J.; McKeague, M.; Zhang, X.; Giamberardino, A.; McConnell, E.; Francis, T.; DeRosa, M.C.; Dumontier, M. Aptamer Base: A collaborative knowledge base to describe aptamers and SELEX experiments. Database: Journal of Biological Databases and Curation. 2012.

    52. 2011

  52. McKeague, M.; Giamberardino, A.; DeRosa, M.C. Advances in aptamer-based biosensors for food safety, Environmental Biosensors. 2011, Vernon Somerset (Ed.) ISBN: 9789533074863, InTech. DOI:10.5772/22350
  53. De Girolamo, A.; McKeague, M.; Miller, J.D.; DeRosa, M.C.; Visconti, A. Determination of ochratoxin A in wheat after clean-up through a DNA aptamer-based solid phase extraction column. Food Chemistry. 2011, 127 (3), 1378-1384.

    54. 2010

  54. McKeague, M.; Bradley, C.R.; De Girolamo, A.; Visconti, A.; Miller, J.D.; Derosa, M.C. Screening and initial binding assessment of fumonisin B(1) aptamers, International Journal of Molecular Sciences. 2010, 11 (12), 4864-4881.
  55. Luo, X.; McKeague, M.; Pitre, S.; Dumontier, M.; Green, J.; Golshani, A.; Derosa, M.C.; Dehne, F. Computational approaches toward the design of pools for the in vitro selection of complex aptamers, RNA. 2010, 16 (11), 2252-2262.